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DOI: 10.17587/it.25.602-608 Yu. A. Mezentsev, Doctor of Technical Sciences, Professor, e-mail: mesyan@yandex.ru, The NP-hard clustering problem as applied to the data of neurophysiological studies (indicators of postoperative cognitive dysfunction) is considered. Variants of the problem of clustering in the form of mixed integer programming, including the use of continuous relaxation, reducing the complexity of solutions without loss of accuracy are given. The results of computational experiments on real data using the software implementation of the algorithm of binary cuts and branch are presented. They demonstrate the high efficiency of the developed toolkit. P. 602–608 Acknowledgements: This work was supported by the Russian Foundation for Basic Research, project no. 19-29-01017.
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